The protection of seed oil of Hippophae rharmnoides on ischemic cerebral infarction in rats / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 548-550, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-282270
ABSTRACT
<p><b>OBJECTIVE</b>To study the protection of seed oil of Hippophae rhamnoides on ischemic cerebral infarction in rats and the mechanism of the action.</p><p><b>METHOD</b>Focal cerebral ischemia model was made by middle cerebral artery occlusion(MCAO) in rats. Behavior obstacles of rats were observed. Cerebral infarction volume was determined by Megnetic Resonance Imaging(MRI).</p><p><b>RESULT</b>Seed oil of Hippophae rhamnides 0.7 and 0.35 g.kg-1 could markedly reduce infarction volume after occlusion of middle cerebral artery in rats and also could ameliorate the behavior obstacles of rats.</p><p><b>CONCLUSION</b>These results suggested that seed oil of Hippophae rhamnoides had distinct protection to ischemic cerebral infarction in rats.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Plants, Medicinal
/
Seeds
/
Behavior, Animal
/
Plant Oils
/
Drugs, Chinese Herbal
/
Chemistry
/
Rats, Wistar
/
Neuroprotective Agents
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2003
Type:
Article
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