Comparative study on the efficacy of Yiweining and Gestrinone for post-operational treatment of stage III endometriosis / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 218-220, 2006.
Article
in En
| WPRIM
| ID: wpr-282474
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the clinical efficacy and safety of Yiweining (YWN) and gestrinone (GT) in treating post-operational patients of stage III endometriosis (EM-III).</p><p><b>METHODS</b>Fifty-two patients of EM-III after operation were randomly assigned into three groups, the YWN group (20 patients) was treated through oral intake of YWN 200 ml, twice a day; the GT group (19 patients) treated with gestrinone 2.5 mg, twice every week, with the medication starting from the 7th post-operational day and lasting for 6 months. The control group (13 patients) was untreated. Six months was one therapeutic course, and follow-up study was carried out in the 6 - 30 months after the end of the medication.</p><p><b>RESULTS</b>The recurrence rate in the YWN group and the GT group were 5.0% and 5.3% respectively, showing insignificant difference between the two groups, but they were lower than that in the control group (30.7%, P < 0.05). Besides, the adverse reaction rate in the YWN group was lower than that in the GT group (10.0% vs 31.6%, P < 0.05).</p><p><b>CONCLUSION</b>Application of YWN to prevent the post-operational recurrence of endometriosis is effective and safe, and its efficacy is similar to that of GT.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Postoperative Complications
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Progestins
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General Surgery
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Drugs, Chinese Herbal
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Gestrinone
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Administration, Oral
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Follow-Up Studies
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Treatment Outcome
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Pregnancy Rate
Type of study:
Observational_studies
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Prognostic_studies
Limits:
Adult
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Female
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Humans
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Pregnancy
Language:
En
Journal:
Chinese journal of integrative medicine
Year:
2006
Type:
Article