Multivariate analysis of the risk factors of cytomegalovirus pneumonia after renal transplantation / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1182-1184, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-282587
ABSTRACT
<p><b>OBJECTIVE</b>To identify the risk factors for cytomegalovirus (CMV) pneumonia after renal transplantation and investigate the early precaution measures.</p><p><b>METHODS</b>A retrospective study was conducted in a group of 28 patients undergoing renal transplantation who were readmitted because of CMV pneumonia between Jan, 2005 and Dec, 2007. Chi-square test and multivariate logistic regression were used to identity the significant risk factors.</p><p><b>RESULTS</b>Seven factors, namely recipient age, acute graft rejection, pre-transplantation dialysis, delayed graft function recovery, recipient peak PRA level, donor CMV positivity and the use of MMF were found to significantly correlate to post-transplant CMV pneumonia. Multivariate logistic regression further confirmed that donor CMV IgG positivity, acute graft rejection and pre-transplantation dialysis for over 6 months were independent factors to predict the occurrence of CMV pneumonia.</p><p><b>CONCLUSIONS</b>Acute graft rejection control, appropriate donor selection and shortened dialysis before the transplantation can be crucial factors to reduce the incidence of CMV pneumonia after renal transplantation.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia, Viral
/
Postoperative Complications
/
Multivariate Analysis
/
Retrospective Studies
/
Risk Factors
/
Age Factors
/
Renal Dialysis
/
Kidney Transplantation
/
Cytomegalovirus Infections
/
Graft Rejection
Type of study:
Etiology study
/
Observational study
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Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2009
Type:
Article
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