Expression of aquaporin-1 in human oligohydramnios placenta and fetal membranes / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1130-1132, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-282603
ABSTRACT
<p><b>OBJECTIVE</b>To detect aquaporin-1 mRNA (AQP1) expression in human oligohydramnios placenta and fetal membranes.</p><p><b>METHODS</b>Placenta and fetal membranes samples were obtained from 5 women with oligohydramnios and 5 with normal amniotic fluid volume. AQP-1 mRNA expression in the tissue samples was detected by semi-quantitative RT-PCR.</p><p><b>RESULTS</b>The expression of AQP1 mRNA was significantly lower in oligohydramnios placenta than in normal pregnancy placenta at term (P<0.05), and also significantly lower in oligohydramnios fetal membranes than in normal fetal membranes at term (P<0.05).</p><p><b>CONCLUSION</b>Alterations in AQP1 mRNA expressions in human placenta and fetal membranes may play an important role in the disorder of maternal-fetal fluid exchange and amniotic fluid volume.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Placenta
/
Pregnancy Trimester, Third
/
RNA, Messenger
/
Oligohydramnios
/
Aquaporin 1
/
Extraembryonic Membranes
/
Genetics
/
Metabolism
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS