Studies on chemical constituents of Rabdosia serra / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of aerial part of Rabdosia serra.</p><p><b>METHOD</b>The compounds were isolated by extraction, coloum chromatography over silica gel and ODS, and preparative HPLC. Their structures were identified by various spectroscopic methods including MS, IR, 1D and 2D NMR data.</p><p><b>RESULT</b>Six compounds were isolated from R. serra and were characterized as ent-1alpha, 7alpha, 14beta, 20-tetrahydroxy-11, 16-kauradien-15-one (1), kamebakaurin (2), dihydrokamebakaurin (3), rabdoinflexin A (4), daucosterol( 5), and beta-sitosterol (6).</p><p><b>CONCLUSION</b>Compound 1 is a new compound, and coumpound 3 was obtained from this plant for the first time.</p>