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Rubrofusarin glucosides of Berchemia polyphylla var. leioclada and their scavenging activities for DPPH radical / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2084-2087, 2011.
Article in Chinese | WPRIM | ID: wpr-283253
ABSTRACT
<p><b>OBJECTIVE</b>To study the rubrofusarin glucosides from whole plants of Berchemia polyphylla var. leioclada, and their scavenging activities for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.</p><p><b>METHOD</b>The chemical constituents were isolated and purified via repeated silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by spectral analysis and the compounds were tested for their scavenging activities on DPPH radical.</p><p><b>RESULT</b>Three rubrofusarin glucosides compounds were isolated and identified as rubrofusarin-6-O-beta-D-glucopyranoside (1), rubrofusarin-6-O-beta-D-(6'-O-acetyl) glucopyranoside (2), rubrofusarin-6-O-alpha-L-rhamnosyl-(1-6) -O-beta-D-glucopyranside (3). Three isolated compounds showed strong scavenging activities on DPPH radical, the concentration of half elimination ratio( micromol x L(-1)) of VitC and Compounds 1-3 were 18.2, 40.5, 23.3 and 13.6, respectively.</p><p><b>CONCLUSION</b>Compounds 1-3 were isolated from this plant for the first time and compound 2 was a new compound. They showed significant antioxidant activity, and the scavenging activity of compound 3 was a little stronger than that of VitC.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Picrates / Pyrones / Biphenyl Compounds / Chemistry / Free Radical Scavengers / Nuclear Magnetic Resonance, Biomolecular / Rhamnaceae / Glucosides / Metabolism Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Picrates / Pyrones / Biphenyl Compounds / Chemistry / Free Radical Scavengers / Nuclear Magnetic Resonance, Biomolecular / Rhamnaceae / Glucosides / Metabolism Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2011 Type: Article