Clinical analysis of gastrointestinal stromal tumor: a report of 29 patients / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 139-141, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-283366
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical manifestations, diagnosis and treatment of gastrointestinal stromal tumor (GIST).</p><p><b>METHODS</b>Clinicopathological data of 29 cases with GIST from 2003 to 2005 were retrospectively analyzed.</p><p><b>RESULTS</b>The most common clinical manifestations were abdominal pain, distention or discomfort in 16 cases (55.2%), abdominal mass in 9 (31.0%), melena and hematemesis in 5 cases (17.2%). The tumor was located in the stomach in 16 cases, the small intestine in 9, the colorectum in 2, the esophagus in one, and the duodenum in one case. All the cases underwent operation, included total gastrectomy in one case, subtotal gastrectomy in 8, partial gastrectomy in 4, local excision of the tumor in 5 cases, partial small intestine resection in 9 and right colectomy in 2 cases. The resection rate was 100% and no complication and death occurred. The positive rates of CD117(+) and CD34(+) were 93.1% and 51.7% respectively. After follow up from one to 2 years after operation, 2 cases died of tumor recurrence and metastasis, the others survived.</p><p><b>CONCLUSIONS</b>Immunohistochemical examinations of CD117 and CD34 are important diagnostic markers. Surgery is the main method of final diagnosis and treatment.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
General Surgery
/
Biomarkers
/
Retrospective Studies
/
Follow-Up Studies
/
Proto-Oncogene Proteins c-kit
/
Antigens, CD34
/
Gastrointestinal Stromal Tumors
/
Diagnosis
/
Gastrectomy
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2006
Type:
Article
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