Detection of monoamine transmitters in serum of macaque by high performance liquid chromatograghy with electrochemical detector / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 703-705, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-283402
ABSTRACT
<p><b>OBJECTIVE</b>To develop an HPLC-ECD for the determination of monoamine transmitters in serum of macaque.</p><p><b>METHOD</b>The analysis was carried out on a ZORBAX SB-C18 column (4.6 mm x 250 mm, 5 microm) eluted with a mobile phase of methanol-water (1882) at a flow rate of 0.9 mL x min(-1).</p><p><b>RESULT</b>The recoveries of NE, E, DA, 5-HT were 97.0%, 97.8%, 99.5%, 100.3%, RSD was 0.22%-0.93%, and the repeatability was good.</p><p><b>CONCLUSION</b>The results prove that the method is simple, fast, accurate and can be used to determine simultaneously the concentration of monoamine transmitters in serum of macaque.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Premenstrual Syndrome
/
Biogenic Monoamines
/
Dopamine
/
Epinephrine
/
Serotonin
/
Norepinephrine
/
Reproducibility of Results
/
Chromatography, High Pressure Liquid
/
Electrochemistry
Type of study:
Diagnostic study
Limits:
Animals
/
Female
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2007
Type:
Article
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