Sodium dodecyle sulphate polyacrylamide gel electrophoresis of whole salivary proteins from patients with adult periodontitis / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>This study was intended to determine the salivary protein factors related to adult periodonititis.</p><p><b>METHODS</b>Twenty-five patients with adult periodontitis (AP group) and twenty-five normal controls (NC group, 25) were adopted in the study. Salivary protein composition in unstimulated whole saliva samples obtained before and after basic treatment was analyzed by SDS-PAGE.</p><p><b>RESULTS</b>The volume of proteins with 66 kD, 18 kD, 15 kD, 13 kD in AP group before treatment were all remarkably higher than those in NC group. In addition, 51 kD, 34 kD, 19 kD, 17 kD protein bands were more frequently observed in AP group by comparison with NC group. However, after initial therapy, all the variables mentioned above decreased remarkably.</p><p><b>CONCLUSION</b>The results demonstrated that protein bands with 18 kD, 15 kD, 13 kD might be closely related to the occurrence and recovery of periodontitis, and serum-derived proteins in saliva increased in patients with adult periodontitis.</p>