A Case of Unilateral Multiple Piloleiomyoma, of which the Pain was Ameliorated with Oral Nifedipine / 대한피부과학회지

ABSTRACT

We report a case of multiple piloleiomyoma in a 50-year-old man. About 30 years ago, multiple red colored firm papules with pain developed on the left lower leg. The skin lesions gradually increased in number and size arranging in a group. Some lesion became more painful after cold exposure. About a few years ago, new lesions developed on the left back and flank abdomen. The histologic findings showed poorly demarcated and were composed of interlacing bundles of smooth muscle fibers with varying amounts of collagen bundles being intermingled. Masson's trichrome and smooth muscle actin stain showed typical leiomyoma, and s-100 stains revealed an increased amount of nerve fibers interlacing within muscle fibers and the surrounding tissue. We diagnosed our case as unilateral multiple piloleiomyoma arising from arrector pilorum muscle. Pain was ameliorated with oral nifedipine alone.