Stability of physical state on compound hawthorn dropping pills / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2474-2478, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-283860
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the stability of physical state with accelerate test and dropping in process before and after on compound hawthorn dropping pills.</p><p><b>METHOD</b>Scanning electron microscope, TG-DTA, FT-IR and XRD were used.</p><p><b>RESULT</b>The active components presented amorphous, tiny crystal and molecular state in dropping pills, and it had no obvious reaction between PEG 4000 and active components. With time prolonging, a little of active components changed from amorphous state to tiny crystal or molecular state.</p><p><b>CONCLUSION</b>Solid dispersion improved the stability and dissolution of compound hawthorn dropping pills.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Solubility
/
Drugs, Chinese Herbal
/
Microscopy, Electron, Scanning
/
Chemistry
/
Spectroscopy, Fourier Transform Infrared
/
Crataegus
/
Drug Compounding
/
Drug Stability
/
Methods
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
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