Comparison of whole body diffusion weighted magnetic resonance imaging and somatostatin receptor scintigraphy for oncogenic osteomalacia / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 437-442, 2012.
Article
in English
| WPRIM
| ID: wpr-284353
ABSTRACT
<p><b>OBJECTIVE</b>To compare the accuracy of whole body diffusion weighted magnetic resonance imaging (WB-DWI) with that of somatostatin receptor scintigraphy (SRS) in the detection and localization of the lesions in patients with oncogenic osteomalacia (OOM).</p><p><b>METHODS</b>Totally 6 patients with clinically suspected oncogenic osteomalacia were enrolled. All of them underwent WB-DWI and SRS within 2 weeks to evaluate the possible presence of tumors that lead to osteomalacia. Surgical and pathological findings were considered as the gold standard. The sensitivity, specificity, and accuracy were calculated.</p><p><b>RESULTS</b>Pathology confirmed the diagnosis of two soft tissue tumors (including 1 angiolipoma and 1 mesenchymal tumor) and one bone tumor of malignant neurofibroma. The sensitivity, specificity, and accuracy in the identification of lesions in patients with oncogenic osteomalacia were 33.33%, 100%, 66.67% for WB-DWI and 33.33%, 66.67%, 50% for SRS (P>0.05).</p><p><b>CONCLUSION</b>For adult patients with osteomalacia, WB-DWI and SRS can provide mutually supportive data and be used for identifying potential oncogenic osteomalacia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bone Neoplasms
/
Sensitivity and Specificity
/
Receptors, Somatostatin
/
Diffusion Magnetic Resonance Imaging
/
Diagnosis
/
Whole Body Imaging
/
Methods
/
Neoplasms, Connective Tissue
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2012
Type:
Article
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