Study on chemical constituents in rhizome of Securidaca inappendiculata / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 780-782, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-284394
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of Securidaca inappendiculata.</p><p><b>METHOD</b>Column chromatographic techniques were applied to isolate constituents. A combination of MS and NMR spectroscopy was used to identify structures of constituents.</p><p><b>RESULT</b>Seven compounds were isolated from the CHCl3 fraction and their structures were elucidated as 3, 4-dihydroxybezoic acid (1), 3-hydroxy-4-methoxylbenzoic acid (2), coniferaldehyde (3), 7-hydroxy-1, 2, 3, 8-tetrame thoxyxanthone (4), 1, 3, 8-trihydroxy-4-methoxyxanthone (5), 1, 3, 8-trihydroxy-2-methoxyxanth-one (6), 1, 3, 6-trihydroxy-2,7-dimethoxyxanthone (7).</p><p><b>CONCLUSION</b>Compounds 1-6 were isolated for the first time from the genus. The antioxidant activities of compounds 3-6 were assayed by the method of DPPH and compound 3 showed the IC50 value of 4.14 microg x mL(-1).</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Inhibitory Concentration 50
/
Spectrometry, Mass, Electrospray Ionization
/
Rhizome
/
Securidaca
/
Antioxidants
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
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