Studies on expectorant compounds in volatile oil from root and rhizome of Aster tataricus / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 281-283, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-284418
ABSTRACT
<p><b>OBJECTIVE</b>To research the expectorant components in volatile oil from the root and rhizome of Aster tataricus.</p><p><b>METHOD</b>GC-MS was applied to isolate and identify the compounds. In addition, TLC was used to isolate compound, and its structure was elucidated on the basis of spectral data analysis. At the same time, its expectorant effect was observed by method of the excretion quantity of phenol red in trachea of mice.</p><p><b>RESULT</b>Seven compounds were isolated and identified by GC-MS, they were (R)(-)-p-menth-1-en-4-ol (1), 2-undecanone (2), n-decanoic acid (3), (-)-spathulenol (4), hexahydrofamrnesyl acetone (5), hexadecanoic acid (6), and cis-9, cis-12-octaecadienoic acid (7). A known compound 1-acetoxy-2-ene(E)-4,6- decandiyne was isolated from the root and rhizome of A. tataricus, and it was shown to have expectorant effect.</p><p><b>CONCLUSION</b>1-Acetoxy-2-ene(E) -4,6- decandiyne, a main compound in volatile oil, had been found to have expectorant effect.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Oils, Volatile
/
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Plant Roots
/
Rhizome
/
Aster Plant
/
Expectorants
/
Gas Chromatography-Mass Spectrometry
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS