Chemical constituents from stems of Schisandra propinqua / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 521-523, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-284453
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents in the stems of Schisandra propinqua and evaluate their effects on proliferation of vascular smooth muscle cells (VSMCs) in vitro by MTT assay.</p><p><b>METHOD</b>The compounds were isolated and purified by various column chromatographic techniques and their structures were elucidated on the basis of spectral analysis (ESI-MS, 1H-NMR, 13C-NMR).</p><p><b>RESULT</b>Five compounds were isolated and identified as galgravin (1), veraguensin (2), octadecanoic acid 2, 3-dihydroxypropyl ester (3), hexadecanoic acid 2, 3-dihydroxypropy ester (4), tetracosanoic acid 2, 3-dihydroxypropyl ester (5).</p><p><b>CONCLUSION</b>All the compounds were isolated for the first time from the plant. 1, 2, 5 showed inhibiting effects on vascular smooth muscle cell (VSMCs) proliferation in vitro.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Lignans
/
Plant Stems
/
Spectrometry, Mass, Electrospray Ionization
/
Schisandra
/
Furans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
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