Protective effect and mechanism of ginsenosides on central nerve system of animals / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 89-93, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-284506
ABSTRACT
Progress of studies concerning the protective effect of ginsenoside on central nerve system (CNS) in animals and its mechanism published in recent decade were reviewed in this paper. It showed that ginsenosides could improve the learning capacity and memory in normal, aged animals, as well as in model animals with impaired memory. The mechanism of the protective effect on CNS involves the effects on calcium channel blockade, glutamate and gamma-aminobutyric acid, antiperoxidation, estrogen-like action, nitric oxide and its synthase, also the inhibition on cerebral nerve cell apoptosis and amelioration on mitochondrial dysfunction, etc.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Avoidance Learning
/
Aging
/
Neuroprotective Agents
/
Nitric Oxide Synthase
/
Ginsenosides
/
Therapeutic Uses
/
Drug Therapy
/
Memory
/
Memory Disorders
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2005
Type:
Article
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