Dissecting functional chemome of Xiaoqinglong decoction analogous formulae using network formulaology approach / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2634-2638, 2015.
Article
in English
| WPRIM
| ID: wpr-284763
ABSTRACT
Analogous formulae (AF) refer to a set of traditional Chinese medicine (TCM) formulae sharing similar herbs and/or indications. Dissecting functional chemome of analogous formulae could enhance the understanding of the intrinsic nature of TCM. In this study, taking 5 Xiaoqinglong decoction analogous formulae (XQL AF) including Xiaoqinglong decoction, Mahuang Xingren Shigao Gancao decoction, Mahuang Fuzi decoction, Houpu Mahuang decoction and Daqinglong decoction as example, we systematically investigated the relationship between compounds and indications using network formulaology approach. The functional chemome of XQL AF were revealed by network analysis and molecular docking. This successful application in XQL AF suggests network formulaology could be a useful tool for AF-related research and therefore provide a new way to discover the scientific foundation of Zhang Zhongjing's herbal formulae.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Chemistry, Pharmaceutical
/
Molecular Docking Simulation
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
Language:
English
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article
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