Daily lifestyles and anti-mutagenicity of saliva

ABSTRACT

<p><b>OBJECTIVES</b>The purpose of this study was to investigate the relation between lifestyle and the antimutagenicity of saliva.</p><p><b>METHODS</b>Subjects were 52 healthy female university students. The collection of the saliva samples and the lifestyle measurements were carried out for them. The anti-mutagenicity of the saliva was measured using the umu test.</p><p><b>RESULTS</b>With regard to the lifestyle items, only "nutrient balance" tended to contribute positively to the inhibiting capacity of the saliva on the mutagenicity of AF-2. In addition, there was a significant inverse correlation between the score of 7 other items and the inhibiting capacity of the saliva (r=-0.32; p<0.05). We also found a significant relation between their tea and/or coffee consumption and the inhibiting capacity of the saliva.</p><p><b>CONCLUSIONS</b>These findings suggest that the inhibiting capacity of saliva worked to decrease mutagen levels that were enhanced by poor lifestyle. In addition, "nutrient balance" may contribute to the inhibiting capacity of the saliva independent of 7 other items. With regard to the tea and/or coffee consumption. further studies should be carried out.</p>