Value of diffusion-weighted imaging in diagnosis of lymph node metastasis in patients with cervical cancer / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 73-78, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-285922
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of diffusion-weighted imaging (DWI) in the differentiation of metastatic lymph nodes from non-metastatic lymph nodes in cervical cancer.</p><p><b>METHODS</b>In 65 patients who underwent lymph node dissection for cervical cancer, conventional MRI and DWI examinations were performed before surgery. Of the 1590 total dissected pelvic lymph nodes, 392 enlarged nodes with a short-axis diameter (S )of 5 mm or greater were included for further analysis. Each of the size-based criteria [i.e., S, long-axis diameter (L), and S/L ratio] and apparent diffusion coefficient(ADC)-based criteria (i.e., ADCmin, ADCmean, rADCmin, rADCmean) were compared between metastatic lymph nodes and non-metastatic lymph nodes.</p><p><b>RESULTS</b>There were statistically significant differences between metastatic and non-metastatic lymph nodes in S, L, S/L ratio, ADCmin, ADCmean, rADCmin, and rADCmean (all P<0.0001). The Az of the ADCmin (0.956) was greater than that of the other ADC-based criteria and all size-based criteria. Using ADCmin=759.0×10(-6) mm(2)/s, the sensitivity and specificity for differentiating metastatic from non-metastatic lymph nodes were 95.2% and 92.1%, respectively.</p><p><b>CONCLUSION</b>DWI, particularly ADCmin, is feasible for differentiating metastatic from non-metastatic pelvic lymph nodes in patients with cervical cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Uterine Cervical Neoplasms
/
Sensitivity and Specificity
/
Diffusion Magnetic Resonance Imaging
/
Diagnosis
/
Lymph Nodes
/
Lymphatic Metastasis
Type of study:
Diagnostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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