Effect of Intravenous Intraoperative Esmolol on Pain Management Following Lower Limb Orthopedic Surgery
The Korean Journal of Pain
;
: 198-202, 2015.
Article
in English
| WPRIM
| ID: wpr-28600
ABSTRACT
BACKGROUND:
Lack of proper control of acute postoperative pain often leads to lingering or chronic pain. Several studies have emphasized the role of beta-blockers in reducing postoperative pain. Esmolol is a selective short-acting beta-blocker that produces few side effects. The purpose of this study was to examine the effect of intravenous intraoperative esmolol on postoperative pain reduction following orthopedic leg fracture surgery.METHODS:
In a clinical trial, 82 patients between 20-65 years of age with tibia fractures and American Society of Anesthesiologists (ASA) physical status I & II who underwent surgery were divided into two groups. Group A received esmolol and group B received normal saline. Postoperative pain was measured at three time points entering the recovery unit, and at 3 h and 6 h following surgery, using the Visual Analogue Scale (VAS). A P value of < 0.05 was considered significant.RESULTS:
Mean VAS scores at all three time points were significantly different between the two test groups (P = 0.02, P = 0.0001, and P = 0.0001, respectively). The consumption of pethidine was lower in group A than in group B (P = 0.004) and the duration of its effect was significantly longer in time (P = 0.026).CONCLUSIONS:
Intravenous intraoperative esmolol is effective in the reduction of postoperative pain following leg fracture surgery. It reduced opioid consumption following surgery and delayed patient requests for analgesics.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orthopedics
/
Pain, Postoperative
/
Tibia
/
Tibial Fractures
/
Pain Measurement
/
Lower Extremity
/
Chronic Pain
/
Pain Management
/
Visual Analog Scale
/
Analgesics
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
English
Journal:
The Korean Journal of Pain
Year:
2015
Type:
Article
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