Stem cell therapy for erectile dysfunction / 中华男科学杂志
National Journal of Andrology
;
(12): 827-830, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-286415
ABSTRACT
Erectile dysfunction (ED), as a pathological phenomenon, refers to repeated or sustained difficulty to achieve and maintain sufficient penile erection to complete satisfactory sexual intercourse or sexual activity in male. The erectile reflex interruption induced by cavernous nerve (CN) damage is a direct cause of ED. In addition, the apoptosis of smooth muscle cells and endothelial cells in the corpus cavernosum caused by CN injury, along with the reduction of corpus cavernosum smooth muscle fibers, can increase the incidence of ED. Therefore, early intervention of the pathological process of CN injury and promotion of CN regeneration are essential for the treatment of ED. In recent years, the stem cell therapy for ED has become a focus in clinical research. This article offers an overview on the application of embryonic stem cells, mesenchymal stem cells, muscle-derived stem cells, and adipose stem cells in the treatment of ED.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stem Cells
/
General Surgery
/
Adipocytes
/
Cell Biology
/
Myocytes, Smooth Muscle
/
Stem Cell Transplantation
/
Embryonic Stem Cells
/
Mesenchymal Stem Cells
/
Erectile Dysfunction
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2012
Type:
Article
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