Shengjing prescription improves semen parameters of oligoasthenozoospermia patients: efficacy and mechanism / 中华男科学杂志
National Journal of Andrology
;
(12): 764-767, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-286444
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical efficacy of Shengjing prescription for oligoasthenozoospermia and its action mechanism.</p><p><b>METHODS</b>We equally assigned 120 patients with oligoasthenozoospermia to receive Shengjing prescription (treatment group) and vitamin E (control group), respectively, for 12 weeks. Before and after the treatment, were obtained sperm concentration, sperm motility, the percentage of morphologically normal sperm, the levels of serum follicle-stimulating hormone (FSH), testosterone (T) and luteinizing hormone (LH), sperm DNA fragmentation index (DFI), the percentage of hypotonic swelling sperm, and the levels of seminal plasma elastase, x-glucosidase, fructose, zinc and acrosin.</p><p><b>RESULTS</b>Compared with vitamin E, Shengling prescription significantly improved sperm concentration, motility and morphology (P < 0.01), decreased the serum FSH level, elevated the serum T level (P <0. 01) , reduced DFI and seminal plasma elastase, and increased the percentage of hypotonic swelling sperm as well as the levels of seminal plasma cx-glucosidase, fructose, zinc and acrosin.</p><p><b>CONCLUSION</b>Shengjing prescription improves semen parameters of patients with oligoasthenozoospermia at multiple levels and through multiple channels.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sperm Count
/
Sperm Motility
/
Vitamin E
/
Drugs, Chinese Herbal
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Asthenozoospermia
/
Infertility, Male
/
Phytotherapy
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2012
Type:
Article
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