Mortality and survival analysis of liver cancer in China / 中华肿瘤杂志

ABSTRACT

<p><b>OBJECTIVE</b>Based on the cancer registry data to analyze the mortality and survival of liver cancer in China.</p><p><b>METHODS</b>Liver cancer data of 2011 were retrieved from the National Cancer Registry Database.Liver cancer deaths were estimated using age-specific rate by areas and gender according to the national population in 2011. Mortality data from 22 cancer registries during 2000-2011 were used to analyze the mortality trend, and data from 17 cancer registries during 2003-2005 were used for survival analysis.</p><p><b>RESULTS</b>The estimates of liver cancer deaths were about 322 thousand in 2011 with a crude mortality rate of 23.93/10(5).There was an increasing trend of crude mortality rate of liver cancer during 2000-2011 in 22 Chinese cancer registries with an average annual percentage change of 0.7% (95%CI 0.2%-1.2%), 1.1% in urban and 0.4% in rural areas. After age standardization with Segi's population, the mortality rate was significantly decreased, with an APC of -2.3%, -1.9% in urban and -2.2% in rural populations. The 5-year age standardized relative survival was 10.1% (95%CI 9.5% to 10.7%), and the 1-, 3- and the 5-year observed survival rates were 27.2%, 12.7%, and 8.9%, respectively.</p><p><b>CONCLUSION</b>Liver cancer is a major cancer threatening people's lives and health in China, and the liver cancer burden is still high.</p>