Research progress of prophylactic cranial irradiation for locally advanced non-small cell lung cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 1-3, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-286765
ABSTRACT
As multi-modality treatments are now able to ensure better local control and a lower rate of extra-cranial metastasis, brain metastasis has become a major concern in locally advanced non-small cell lung cancer (LA-NSCLC). Prophylactic cranial irradiation (PCI) is now a standard treatment for patients with small cell lung cancer (SCLC), it decreases the incidence of brain metastases and increases the survival rate. Despite the relatively high incidence of brain metastases in LA-NSCLC, the role of PCI in patients treated with radical intent has not been established yet. The objective of this systematic review was to establish whether PCI prevents the development of brain metastasis and increases survival in LA-NSCLC patients, the characteristics of the benefit patients, the tolerance and toxicity, the effective dose and timing of PCI. The main concern in this review is to establish the definitive role of PCI in the treatment of locally advanced NSCLC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain Neoplasms
/
Survival Rate
/
Cranial Irradiation
/
Carcinoma, Non-Small-Cell Lung
/
Biomedical Research
/
Small Cell Lung Carcinoma
/
Lung Neoplasms
Type of study:
Systematic reviews
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2016
Type:
Article
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