Study of the genes expression of SCD-2 and B-FABP in the mice brain of exercise-induced fatigue by genechip cDNA microarray / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>By genechip cDNA microarray, the genes expressions of Stearoyl-coenzyme A desaturase (Scd-2) and brain fatty acid-binding protein (B-FABP) were studied in the central nervous system (CNS) of the mice to discuss the mechanism of exercise-induced fatigue.</p><p><b>METHODS</b>Building the model of fatigued animal and using the genechip cDNA microarray, the genes expressions were analyzed between the control group and fatigue group mice.</p><p><b>RESULTS</b>The genes expression of Scd-2 and B-FABP were obvious different in the brain of fatigued group mice than of control group.</p><p><b>CONCLUSION</b>Exercise-induced nerve center fatigue is correlated with genes expressions of lipid metabolism.</p>