Experimental study of the effects of puerarin on biological characters of osteoblasts in vitro / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1947-1949, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-287288
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of puerarin on cell proliferation, differentiation, maturation and mineralization in cultured rat osteoblasts.</p><p><b>METHOD</b>Osteoblasts from craniums of newly born SD rats were cultured in vitro. MTT, PNPP and ARS were used to observe the proliferation, activity of ALP and the number of mineral node of cultured osteoblasts in vitro.</p><p><b>RESULT</b>It was found that puerarin had the effect on stimulating cell proliferation, activity of ALP and the number of mineral node of cultured osteoblasts (P < 0.01 or P < 0.05).</p><p><b>CONCLUSION</b>Puerarin can promote proliferation, differentiation, maturation and mineralization of the osteoblasts in vitro.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoblasts
/
Pharmacology
/
Skull
/
Calcification, Physiologic
/
Cell Differentiation
/
Cells, Cultured
/
Rats, Sprague-Dawley
/
Cell Biology
/
Cell Proliferation
/
Alkaline Phosphatase
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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