Advances in the studies of the dysbindin gene in schizophrenia / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 175-178, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-287430
ABSTRACT
Recent reports indicate that the dysbindin gene located on chromosome 6p22.3 is a major susceptibility gene for schizophrenia. In the brain, the dysbindin gene may influence glutamatergic neurotransmission by multiple post- and pr- synaptic mechanisms. This paper reviews the research progress on the dysbindin gene in schizophrenia, including the dysbindin gene and its product, the possible pathogenic mechanisms, the association study of the dysbindin gene with schizophrenia, and the cognitive decline caused by the dysbind in variations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Physiology
/
Schizophrenia
/
Brain
/
Carrier Proteins
/
Cognition Disorders
/
Genetic Predisposition to Disease
/
Polymorphism, Single Nucleotide
/
Dystrophin-Associated Proteins
/
Dysbindin
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2009
Type:
Article
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