Study on the value of Helieobacter pylori (H. pylori) stool antigen immunocard STAT in the diagnosis of H. pylori infection: a meta-analysis / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 71-74, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-287816
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the accuracy of the Helicobacter pylori (H. pylori) stool antigen (HpSA) test and ImmunoCard STAT HpSA in the primary diagnosis of H. pylori infection.</p><p><b>METHODS</b>We searched Medline (1966-2007.4), EMbase (1985-2007.4), Chinese Journals Full-text Database (CJFD) (1994-2007) etc. to identify Clinical Trials of ImmunoCard STAT HpSA for the primary diagnosis of H. pylori infection. Meta-analysis was conducted using the method recommended by The Cochrane Collaboration Center.</p><p><b>RESULTS</b>Eleven trials were included with pooled sensitivity, pooled specificity as 0.93 (95% CI 0.91-0.94), 0.93 (95% CI 0.90- 0.95), respectively. Pooled positive likelihood ratio and pooled negative likelihood ratio were 12.01 (95% CI 8.90-16.19), 0.08 (95% CI 0.07-0.11), respectively with the pooled diagnostic odds ratio as 160.14(95% CI100.43-255.34). The area under the summary receiver operating characteristic (SROC) was 0.974 +/- 0.005.</p><p><b>CONCLUSION</b>ImmunoCard STAT HpSA appeared to be an accurate non-invasive method for the initial diagnosis of H. pylori infection.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reagent Kits, Diagnostic
/
Virulence
/
Helicobacter pylori
/
Helicobacter Infections
/
Sensitivity and Specificity
/
Diagnosis
/
Allergy and Immunology
/
Feces
/
Microbiology
/
Antigens, Bacterial
Type of study:
Diagnostic study
/
Systematic reviews
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2008
Type:
Article
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