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Uterine Cervix Metastasis in Lung Adenocarcinoma with Anaplastic Lymphoma Kinase Rearrangement
Soonchunhyang Medical Science ; : 142-145, 2015.
Article in English | WPRIM | ID: wpr-28803
ABSTRACT
The importance of anaplastic lymphoma kinase (ALK) as an oncogene in non-small cell lung cancer (NSCLC) has emerged as a major concern due to a dramatic clinical effect of targeted therapy. As compared with the research for targeted therapy, the study about clinicopathological characteristics for ALK positive NSCLC hasn't been worked enough. Here, we describe a 35-year-old woman diagnosed with stage IVb NSCLC with ALK rearrangement. During evaluating her disease, a metastatic lesion to uterine cervix was found. Although lung cancer metastasis to female genital tract is rare, we also present case series that show a metastasis to the female genital tract in NSCLC with ALK rearrangement. These case series could suggest that ALK positive NSCLC has distinct metastatic pattern.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Oncogenes / Phosphotransferases / Adenocarcinoma / Glycogen Storage Disease Type VI / Cervix Uteri / Carcinoma, Non-Small-Cell Lung / Lung / Lung Neoplasms / Lymphoma / Neoplasm Metastasis Limits: Adult / Female / Humans Language: English Journal: Soonchunhyang Medical Science Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Oncogenes / Phosphotransferases / Adenocarcinoma / Glycogen Storage Disease Type VI / Cervix Uteri / Carcinoma, Non-Small-Cell Lung / Lung / Lung Neoplasms / Lymphoma / Neoplasm Metastasis Limits: Adult / Female / Humans Language: English Journal: Soonchunhyang Medical Science Year: 2015 Type: Article