Uterine Cervix Metastasis in Lung Adenocarcinoma with Anaplastic Lymphoma Kinase Rearrangement
Soonchunhyang Medical Science
;
: 142-145, 2015.
Article
in English
| WPRIM
| ID: wpr-28803
ABSTRACT
The importance of anaplastic lymphoma kinase (ALK) as an oncogene in non-small cell lung cancer (NSCLC) has emerged as a major concern due to a dramatic clinical effect of targeted therapy. As compared with the research for targeted therapy, the study about clinicopathological characteristics for ALK positive NSCLC hasn't been worked enough. Here, we describe a 35-year-old woman diagnosed with stage IVb NSCLC with ALK rearrangement. During evaluating her disease, a metastatic lesion to uterine cervix was found. Although lung cancer metastasis to female genital tract is rare, we also present case series that show a metastasis to the female genital tract in NSCLC with ALK rearrangement. These case series could suggest that ALK positive NSCLC has distinct metastatic pattern.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oncogenes
/
Phosphotransferases
/
Adenocarcinoma
/
Glycogen Storage Disease Type VI
/
Cervix Uteri
/
Carcinoma, Non-Small-Cell Lung
/
Lung
/
Lung Neoplasms
/
Lymphoma
/
Neoplasm Metastasis
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Soonchunhyang Medical Science
Year:
2015
Type:
Article
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