Clinical and histo-pathological characteristics of 2874 cases with chronic kidney diseases in Southern parts of Hebei province / 中华流行病学杂志

ABSTRACT

Objective The aim of this study was to analyze the characteristics ot patients with chronic kidney disease (CKD) in Southern parts of Hebei province.Methods Records of 2874 CKD patients during January,2008 to May,2011 were retrospectively reviewed.Demographic,clinical and histo-pathological data were analyzed and compared to ones from the past five years.Results The age distribution of the groups was between 16 and 84 years old,with 62.39％ of them between 20 and 50.All patients underwent renal biopsy that with primary glomerulonephritis occurring in 1966 cases (68.41％),secondary glomerulonephritis in 826 cases (28.74％).The frequently seen pathological patterns were IgA nephropaty ( IgAN ),membranous nephropathy (MN) and minimal change disease (MCD) in proper order in the former group while Henoch-Schonlein purpura nephritis (HSPN) and lupus nephritis (LN) were seen in the latter group.Comparing to data of the past five years,the incidence rates of MN,MCD and HBV-GN increased to 16.84％,15.73％and 4.41％ respectively,but all IgAN,HSPN and LN had respectively decreased to 24.70％,5.50％ and 6.65％.MN,IgAN,MCD were commonly appeared in histo-pathological patterns among patients over 50 years of age.Conclusion IgAN was still the most commonly seen renal disease.Compared to data of the past five years,the incidence rates of MN,MCD and HBV-GN showed an increase at different levels.Epidemiological and pathological pattern of patients with CKD in Southern Hebei province had only mild changes over the last 3 years.