Clinicopathologic characteristics of sporadic renal hemangioblastoma / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 679-682, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-288237
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathological characteristics of sporadic renal hemangioblastoma.</p><p><b>METHODS</b>Two cases of sporadic renal hemangioblastoma were studied by histological and immunohistochemical staining, along with review of the literature.</p><p><b>RESULTS</b>Both cases were presented with a renal mass during annual physical examination with an age of 40 and 45 years, respectively. The lesions located in the middle portion of the kidney with a sharp tumor border. Histopathologically, the tumors were characterized by two major components capillary and stromal cells. Immunohistochemically, the stromal cells were positive for vimentin, NSE, S-100 protein and inhibin-α, and negative for CK, HMB45, Melan A, EMA, CD56 and syn. Both tumors showed a very low level of Ki-67 labeling. The endothelial cells were positive for CD34.</p><p><b>CONCLUSION</b>Sporadic renal hemangioblastoma is a rare benign neoplasm, the diagnosis of which is based on the characteristic follicular architecture and an exclusion of other carcinomas of the kidney.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Phosphopyruvate Hydratase
/
General Surgery
/
Vimentin
/
Diagnostic Imaging
/
Immunohistochemistry
/
Carcinoma, Renal Cell
/
S100 Proteins
/
Tomography, X-Ray Computed
/
Follow-Up Studies
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Pathology
Year:
2013
Type:
Article
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