Extended transsphenoidal operation for giant and invasive pituitary adenomas / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1548-1550, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-288549
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the possibility of extended transsphenoidal approach for removing the giant and invasive pituitary adenomas.</p><p><b>METHODS</b>The clinical data of 64 cases with giant and invasive pituitary adenoma treated by extended transsphenoidal approach were studied retrospectively.</p><p><b>RESULTS</b>Among 64 patients, 51 had total resection and 13 had subtotal resection. 26 patients occurred transient diabetes insipidus, 5 patients with transient cerebrospinal rhinorrhoea and 1 patient occurred acute hypopituitarism postoperatively. There were no death or intracranial infection. After operation, 8 patients get radiotherapy, 6 patients receive medicine treatment. Postoperative follow-up period was 3 months to 6 years. No regrowth or recurrence was seen.</p><p><b>CONCLUSION</b>The extended transsphenoidal approach has been proved to a safe and effective method to remove the giant and invasive pituitary adenomas. Patients who got subtotal resection need be close followed-up and receive radiotherapy or medicine treatment it necessary.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pituitary Neoplasms
/
Sphenoid Sinus
/
General Surgery
/
Adenoma
/
Follow-Up Studies
/
Treatment Outcome
/
Neuroendoscopy
/
Hypophysectomy
/
Methods
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2006
Type:
Article
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