Ultrastructure of poly-DL-lactic acid as GTR membrane of soft tissue defects in goats palates / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the ultrastructure changes of PDLLA as GTR membrane of soft tissue defects in the palates of goats.</p><p><b>METHODS</b>To establish penetrating rectangle palate defects in 8 goats. PDLLA membranes were implanted into the defect areas to guide the regeneration of the soft tissue defects. In 1, 2, 4, 6 months after the operation, the membranes were observed with scanning electron microscope.</p><p><b>RESULTS</b>The surface of PDLLA membrane was regular network before implantation. 1 month after the implantation, the edge of network became blunt. 2 months after the implantation, the surface of PDLLA membrane became coarse and irregular. 4 months after the implantation, PDLLA membrane network collapsed. 6 months after the implantation, PDLLA degraded into scraggly accumulation.</p><p><b>CONCLUSION</b>PDLLA membrane supplies good supporting function during concrescence of the soft tissue defects. PDLLA gradually loses mechanic intensity and is absorbed.</p>