Influencing factors for lymphocyte subsets in children aged 0-6 years / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 1114-1117, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-289522
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the influencing factors for lymphocyte subsets in children 0 to 6 years of age.</p><p><b>METHODS</b>Umbilical artery blood samples from 45 healthy full-term infants and venous blood samples from 79 healthy children between 0 and 6 years were collected. According to the methods of delivery, the full-term infants were divided into vaginal delivery group (n=22) and cesarean section group (n=23). Healthy children were divided into different age groups 28 days to 12 months (n=25), 1-3 years (n=26), and 3-6 years (n=28). Lymphocyte subsets were examined by flow cytometry. The influencing factors including delivery method, sex, and age, which might have an effect on the lymphocyte subsets, were analyzed.</p><p><b>RESULTS</b>There were significant differences in T and Ts cell counts, percentage of B cells, and percentage and count of natural killer (NK) cells between the full-term infants of vaginal delivery and cesarean section (P<0.05). The absolute counts and percentages of different lymphocyte subsets showed no significant differences between males and females in healthy children (P>0.05). The counts of all lymphocyte subsets except Ts and NK cells varied significantly between different age groups (P<0.05).</p><p><b>CONCLUSIONS</b>Lymphocyte subsets in children under 6 years of age are more profoundly affected by age. Delivery method is also a contributing factor in newborn infants. The reference range of lymphocyte subsets in children should be established for different age groups.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reference Values
/
Lymphocyte Subsets
/
Age Factors
/
Sex Characteristics
/
Flow Cytometry
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2014
Type:
Article
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