Cost-utility analysis of comprehensive intervention on epilepsy / 中华流行病学杂志

ABSTRACT

Objective To discuss the cost-utility regarding the effect of comprehensive intervention program on epilepsy.Methods 874 cases with epilepsy were investigated in 9 pilot sites in Hcnan province.Cost of epilepsy comprehensive intervention was calculated based on the research projects of epilepsy prevention and management of rural areas.Disability-adjusted life year (DALY)and quality adjusted life year (QALY) were used as utility index for cost-utility analysis.Results Of the 874 cases,8.58 DALY was lost and 27.95 QALY was obtained per capita in the intervention group (422 cases).The costs per QALY and DALY obtained were 2454.10 and 7995.40 Yuan,respectively.Relative to the non-intervention control group (452 cases),the costs for QALY obtained by the intervention group had reduced.The investment would reduce 21 735.10 Yuan when each additional DALY was saved.Conclusion Epilepsy caused serious economic burden to the society,families and the patients themselves.Comprehensive intervention program could reduce the economic burden of the disease thus yielding high cost-benefit.This program was deserved to be promoted.