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Diabetes mellitus related bone metabolism and periodontal disease / 国际口腔科学杂志·英文版
International Journal of Oral Science ; (4): 63-72, 2015.
Article in English | WPRIM | ID: wpr-290160
ABSTRACT
Diabetes mellitus and periodontal disease are chronic diseases affecting a large number of populations worldwide. Changed bone metabolism is one of the important long-term complications associated with diabetes mellitus. Alveolar bone loss is one of the main outcomes of periodontitis, and diabetes is among the primary risk factors for periodontal disease. In this review, we summarise the adverse effects of diabetes on the periodontium in periodontitis subjects, focusing on alveolar bone loss. Bone remodelling begins with osteoclasts resorbing bone, followed by new bone formation by osteoblasts in the resorption lacunae. Therefore, we discuss the potential mechanism of diabetes-enhanced bone loss in relation to osteoblasts and osteoclasts.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Periodontal Diseases / Bone Diseases / Diabetes Mellitus, Type 1 / Diabetes Mellitus, Type 2 / Metabolism Limits: Humans Language: English Journal: International Journal of Oral Science Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Periodontal Diseases / Bone Diseases / Diabetes Mellitus, Type 1 / Diabetes Mellitus, Type 2 / Metabolism Limits: Humans Language: English Journal: International Journal of Oral Science Year: 2015 Type: Article