The associations of serum gastrin level with Helicobacter pylori infection / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 87-89, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-290187
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the associations of serum gastrin-17 (G-17) concentration with helicobacter pylori (Hp) infection.</p><p><b>METHODS</b>A (13)C-urea breath and ELISA test to determine the Helicobacter pylori status and to detect the serum gastrin concentration was conducted in 242 villagers in Linqu of Shandong Province, a high gastric cancer prevalence area in China.</p><p><b>RESULTS</b>Of 242 subjects, 65 of 111 were found Hp-positive in males (58.56%), compared with 65 of 131 in females (49.62%) (chi(2) = 1.932, P = 0.165). The statistical difference was not observed among different age groups (chi(2) = 4.185, P = 0.123). The average level of G-17 among 242 subjects was (24.43 +/- 25.46) pmol/L and it was statistically higher in females (29.87 +/- 28.18) pmol/L than that in males (18.01 +/- 20.11) pmol/L (Z = -3.618, P < 0.001). However, there was no statistical difference found among age groups (chi(2) = 1.948, P = 0.378). The G-17 level in Hp-negative group (35.50 +/- 30.92) pmol/L was observed significantly higher than in Hp-positive group (14.90 +/- 13.79) pmol/L (Z = 5.368, P = 0.0001).</p><p><b>CONCLUSION</b>The G-17 concentration was found higher in Hp-negative subjects than in Hp-positive subjects, and higher in female than in male, but no difference was found among age groups.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rural Population
/
Blood
/
Gastrins
/
China
/
Epidemiology
/
Sampling Studies
/
Helicobacter pylori
/
Helicobacter Infections
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2007
Type:
Article
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