Analysis of genetic characteristics of wild-type measles viruses in Jilin Province 2005 / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 348-350, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-290260
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the know gene types of main wild type measles virus strains and take measures to control measles in Jilin Province.</p><p><b>METHODS</b>Genetic characterization of 9 measles viruses isolated from 72 throat swabs or urine specimens of measles patients using CDW(150) cells line was studied in Jilin Province in 2005.</p><p><b>RESULTS</b>Sequence analysis of 450 nucleotides of COOH-terminal of nucleoprotein (N) genes of 9 isolates indicated that all were members of H(1) genotype, in which there are 7 strains of H1a and 2 strains of H1b, the H1a subgroup differed from H1b by 2.0% approximately 3.5% at the nucleotide level in the COOH-terminal of the N gene.</p><p><b>CONCLUSIONS</b>The H(1) genotype of wild-type measles viruses should be the main epidemic strain and main pathogen that caused measles outbreaks and sporadic cases in Jilin Province.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virology
/
Molecular Sequence Data
/
Viral Structural Proteins
/
China
/
Epidemiology
/
Genes, Reporter
/
Genes, Viral
/
Genetics
/
Genotype
/
Measles
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2006
Type:
Article
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