Long-term administration of angiotension-converting enzyme inhibitor improves the outcome of chronic heart failure in senile patients / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
;
(6): 257-259, 2002.
Article
in English
| WPRIM
| ID: wpr-290541
ABSTRACT
One hundred and sixteen senile patients (older than 65 years) with chronic heart failure (CHF) were analyzed retrospectively in order to verify if old patients with CHF would benefit from long-term (one year) angiotension-converting enzyme inhibitor (ACEI) treatment. The frequency of drugs (including ACEI, digitalis and diuretic) used was stratified into four degrees accordingly. Development of the CHF was scored with regard to relapse rate and severity of this disease. Stepwise regression analysis was applied to explore the relationship between the scored outcome of CHF and the frequency of individual drug administration. A significant relationship of the scored outcome of CHF to the frequency of ACEI usage but not to digitalis nor to diuretics was found (partial coefficient of the correlation r = 0.42, P = 0.002). It was concluded that the long-term administration of ACEI improves the outcome of CHF in senile patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Angiotensin-Converting Enzyme Inhibitors
/
Chronic Disease
/
Retrospective Studies
/
Treatment Outcome
/
Myocardial Ischemia
/
Drug Therapy
/
Heart Failure
/
Hypertension
Type of study:
Observational study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Year:
2002
Type:
Article
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