Clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 385-387, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-290778
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia.</p><p><b>METHODS</b>Clinical data of 354 patients with colorectal cancer in the Second Affiliated Hospital of Guangzhou Medical College from January 2003 to July 2009 were analyzed retrospectively. Those with hemoglobin(Hb)<120 g/L before surgery were defined as cancer-related anemia.</p><p><b>RESULTS</b>Of the 354 colorectal cancer cases, 195 were males and 159 were females. The median age was 65(range 22-92) years. Preoperative cancer-related anemia tended to be occurred in female(P<0.01) and those with preoperative albumin ≤35 g/L (P<0.01), right colon cancer(P<0.01) and full-thickness invasion(P<0.05). Cox regression analysis showed preoperative cancer-related anemia was an independent unfavorable factor for overall survival (HR=1.60, 95% CI1.05-2.44; P<0.05), but not for disease-free survival (HR=1.43, 95% CI0.97-2.12; P>0.05) in colorectal cancer.</p><p><b>CONCLUSIONS</b>Preoperative cancer-related anemia plays an important role in the development and prognosis of colorectal cancer and great attention should be paid to clinical practice.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
General Surgery
/
Colorectal Neoplasms
/
Retrospective Studies
/
Anemia
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2012
Type:
Article
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