Overview research of uremic ulearance granule treating chronic renal failure / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3651-3655, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-291309
ABSTRACT
The effective bioactivity compositions of uremic clearance granul (UCG) include isoflavonoids, emodin, astragaloside, paeoniflorin, salvianolic acid A, and so on. The effects of UCG treating chronic renal failure (CRF) in clinical pharmacodynamics mainly refer to improve renal function and the complications of CRF. The mechanisms involved in vivo basically include depressing transforming growth factor (TGF)-beta1 over-expression, lessening podocyte injury,inhibiting tubular epithelial myofibroblast transdifferentiation, ameliorating microinflammation status, retarding oxidative stress, and alleviating insulin resistance.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Oxidative Stress
/
Therapeutic Uses
/
Drug Therapy
/
Transforming Growth Factor beta1
/
Genetics
/
Kidney
/
Kidney Failure, Chronic
/
Metabolism
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
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