Clinical and laboratory investigation of four acute myeloid leukemia patients with t(3;3) translocation / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 35-37, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-291456
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical and laboratory characteristics of four acute myeloid leukemia with t(3;3) translocation.</p><p><b>METHODS</b>Bone marrow cell chromosome karyotype analysis were carried out with direct method and short-term culture and R-banding technique.</p><p><b>RESULTS</b>Four AML patients with t(3;3) translocation were identified. They did not obtain complete remission after chemotherapy and the median survival time was 4.5 months.</p><p><b>CONCLUSIONS</b>t(3;3) translocation is a rare chromosome abnormality, which has mostly been found in myeloid leukemia and the prognosis of these patients is poor.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Translocation, Genetic
/
Chromosomes, Human, Pair 3
/
Leukemia, Myeloid, Acute
/
Genetics
/
Karyotyping
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hematology
Year:
2004
Type:
Article
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