Impacts of antiretroviral treatment on drug use and high risk sexual behaviors among HIV-positive MMT clients / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 506-512, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-291588
ABSTRACT
<p><b>OBJECTIVE</b>To explore the impacts of antiretroviral treatment on drug use and high risk sexual behaviors among HIV-positive MMT clients.</p><p><b>METHODS</b>A cross-sectional study was conducted in patients undergoing ART (ART-experienced) and patients not undergoing ART (ART-naive) attending MMT in 5 clinics in Yunnan Honghe and Dehong prefectures in 2014. A questionnaire was designed to collect socio-demographic characteristics, ART and MMT information and sexual and drug use behaviors within 3 months before the investigation was conducted. Logistic regression analysis was conducted to identify the predictors for drug use and risky sexual behaviors.</p><p><b>RESULTS</b>A total of 328 cases were included in the analysis, among which 202 were ART-experienced and 126 were ART-naÏve. Among 152 respondents who were sexually active, 61 (40.1%) reported having unprotected sex (UPS) with their regular partners in the prior 3 months. A total of 57.6% (189/328) of the respondents used drugs in the prior 3 months. Multiple logistic regression analysis revealed that younger than 35 years old (OR = 3.57, 95% CI 1.23-10.37), fertility desire (OR = 4.47, 95% CI 1.49-13.41), partner being HIV-positive (OR = 4.62, 95% CI 1.80-11.86), length of MMT attendance less than 5 years (OR = 2.92, 95% CI 1.14-7.53), agreed that it was necessary to use condom no matter the viral load is high or low (OR = 0.14, 95% CI 0.04-0.51) were protective factors of UPS in the prior 3 months. Multiple logistic regression analysis revealed that being Han (OR = 0.46, 95% CI 0.24-0.89), feeling having good health status (OR = 0.39, 95% CI 0.18-0.85), being enrolled in ART (OR = 0.32, 95% CI 0.17-0.60) were protective factors for drug use in the prior three months, having contact with drug using friends (OR = 4.41, 95% CI 2.31-8.29), having experience of missing an MMT dose (OR = 3.47, 95% CI 1.92-6.29), and not satisfied with current MMT dose (OR = 13.92, 95% CI 3.24-59.93) were risk factors for drug use during the prior three months.</p><p><b>CONCLUSION</b>ART was not associated with risky sexual behavior and drug use in the prior 3 months in this population. Future interventions should promote ART among this population, and provide education at the same time to prevent the emergence of cross infections and drug-resistant strains.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organometallic Compounds
/
Risk-Taking
/
Sexual Behavior
/
Sexual Partners
/
HIV Infections
/
China
/
Cross-Sectional Studies
/
Risk Factors
/
HIV Seropositivity
/
Condoms
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2015
Type:
Article
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