Detection for severe acute respiratory syndrome (SARS) coronavirus RNA in stool of SARS patients / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 90-91, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-291808
ABSTRACT
<p><b>OBJECTIVE</b>To investigate excretion of severe acute respiratory syndrome coronavirus RNA (SARS-CoV) in stool of SARS patients.</p><p><b>METHODS</b>SARS-CoV RNA was detected in stool specimens with fluorescent quantitative polymerase chain reactions (FQ-PCR) in 101 SARS patients on the 10 to 55 days after onset, 27 non-SARS patients and 400 individuals with health check-up.</p><p><b>RESULTS</b>SARS-CoV RNA was positive in stool specimens by FQ-PCR in 58 of 101 SARS patients (57.4%), and all negative in 27 non-SARS patients and 400 healthy individuals. Positive rate of SARS-CoV RNA was 100% (8/8), 67.7% (21/31), 47.4% (27/57) and 40.0% (2/5) on the 10 - 19, 20 - 29, 30 - 39 and 40 - 55 days after onset of fever, respectively, with values of logarithm of SARS-CoV RNA load of 6.06 +/- 2.05, 4.51 +/- 1.23, 3.82 +/- 1.44 and 3.57 +/- 1.25, respectively.</p><p><b>CONCLUSION</b>Positive rate and load of SARS-CoV RNA in stool of SARS patients was the highest at their acute phase, and decreased with the extension of its course.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virology
/
RNA, Viral
/
China
/
Polymerase Chain Reaction
/
Severe Acute Respiratory Syndrome
/
Severe acute respiratory syndrome-related coronavirus
/
Feces
/
Genetics
/
Metabolism
Type of study:
Diagnostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2004
Type:
Article
Similar
MEDLINE
...
LILACS
LIS