The effect of basic fibroblast growth factor (bFGF) on neovascularization and prefabricated flap survival / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 278-279, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-292081
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of basic fibroblast growth factor (bFGF) on neovascularization and prefabricated flap survival.</p><p><b>METHODS</b>Male New-Zealand rabbits weighting 2.0-2.5 kg were used in this study. The experimental model used a prefabricated neck flap, supplied by the transferred and implanted central vascular bundle of the ear. 9 micrograms bFGF and 0.2 ml of normal saline was instilled in the vascular pedicle of the experimental and the control group respectively. After 1, 2, 3 weeks of operation, the neovascularization was studied by confocal laser scanning microscope (CLSM) and flap survival was observed.</p><p><b>RESULTS</b>The neovascularization and survival of the prefabricated flap was different in the experimental and the control groups. The experimental group was better than the control group.</p><p><b>CONCLUSION</b>bFGF treatment improved sprouting of the implanted vessel and the prefabricated flap survival.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
Surgical Flaps
/
Time Factors
/
Fibroblast Growth Factor 2
/
Microscopy, Confocal
/
Neovascularization, Physiologic
/
Graft Survival
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Plastic Surgery
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS