Regulation of ion and ion channels in sperm capacitation / 中华男科学杂志
National Journal of Andrology
;
(12): 170-173, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-292402
ABSTRACT
Ion channels in mammal sperm, including Ca2+, Na+, K+, Cl- and HCO3- channels, each play a key role in the process of sperm capacitation. Ca2+, HCO3- and ROS, as signal molecules, activate soluble adenylyl cyclase (sAC) with the cooperation of cyclic adenosine monophosphate (cAMP), Ca2+ and intracellular pH and, via a cross talk between the cAMP/protein kinase A (PKA) and tyrosine phosphatase signaling pathways, promote the biological effect of sperm capacitation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Sperm Capacitation
/
Signal Transduction
/
Ion Channels
/
Ions
/
Mammals
/
Metabolism
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2009
Type:
Article
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