AZF microdeletions are not related with recurrent spontaneous abortion / 中华男科学杂志
National Journal of Andrology
;
(12): 1099-1102, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-292446
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between azoospermia factor (AZF) microdeletions of the Y-chromosome and recurrent spontaneous abortion.</p><p><b>METHODS</b>We collected 26 chorionic villus samples from abortive male embryos and 51 blood samples from the husbands whose wives had recurrent spontaneous abortion, extracted genomic DNA from the samples and detected 12 STSs in the AZFa, AZFb and AZFc regions of Yq11.2 by amplification multiplex PCR.</p><p><b>RESULT</b>AZF microdeletions were found neither in the chorionic villus samples nor in the blood samples.</p><p><b>CONCLUSION</b>There is no relationship between AZF microdeletions and recurrent spontaneous abortion.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Abortion, Spontaneous
/
Abortion, Habitual
/
Polymerase Chain Reaction
/
Chromosome Deletion
/
Seminal Plasma Proteins
/
Chromosomes, Human, Y
/
Genetic Loci
/
Genetics
/
Methods
Limits:
Female
/
Humans
/
Male
/
Pregnancy
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2008
Type:
Article
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