Analysis of etiological surveillance results of Shigella spp between 2009 and 2010 in Henan province / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 334-337, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-292472
ABSTRACT
<p><b>OBJECTIVE</b>To explore the etiologic characteristics of bacillary dysentery found in Henan province, between year 2009 and 2010.</p><p><b>METHODS</b>In order to explore the distribution of bacterial types, drug susceptibility and the virulence gene carrier situation, 482 strains of Shigella isolated in Henan province between 2009 and 2010 were pathogen-detected and analyzed by serotype screening, anti microbial sensitivity test and PCR methods.</p><p><b>RESULTS</b>The 482 isolated strains were confirmed to be Shigella by both morphological and biochemical tests. The Shigella strains were divided into 13 serotypes in 2 groups, namely Shigella flexneri (B group) accounting for 72.0% (347/482) and Shigella sonnei (D group), accounting for 28.0% (135/482). The detection rate of Serotype F2a, as the dominant type of Shigella flexneri, decreased from 43.4% (106/245) in 2009 to 33.8% (80/237) in 2010; while the detection rate of Shigella sonnei increased from 13.1% (32/245) to 43.5% (103/237) in the same period. The results of microbial sensitivity tests carried out in year 2009 and 2010, both showed that over 98% of the 185 studied strains were resistant to ampicillin (AMP), trimethoprim-pyrimidine (TMP), tetracycline (TE), streptomycin (S) and nalidixic acid (NA).182 strains were recruited in the virulence factors detection, 67.6% (123/182) of which carried Shigella Enterotoxin 1B (set1B), Shigella Enterotoxin 2 (set2), invasive plasmid antigen H (ipaH) or invasion-related virulence factors (ial) and 24.2% (44/182) of which carried 3 virulence factors mentioned above.</p><p><b>CONCLUSION</b>The prevalent serotypes of Shigella in Henan province have changed in recent years. The isolated strains showed high resistance to common antibacterial drugs and generally carried virulence factors.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Shigella
/
Microbial Sensitivity Tests
/
Serotyping
/
China
/
Population Surveillance
/
Epidemiology
/
Prevalence
/
Shiga Toxins
/
Dysentery, Bacillary
/
Genetics
Type of study:
Etiology study
/
Prevalence study
/
Screening study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2012
Type:
Article
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