Effects of electroacupuncture at "Fenglong" (ST 40) on NO, ET and CGRP levels in the rat with hyperlipidemia / 中国针灸
Chinese Acupuncture & Moxibustion
;
(12): 57-60, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-292949
ABSTRACT
<p><b>OBJECTIVE</b>To probe the regulative effect of electroacupuncture (EA) at "Fenglong" (ST 40) on blood lipids in hyperlipidemia (HLP) rats and the mechanism.</p><p><b>METHODS</b>Eighty Wistar rats were randomly divided into a normal group (fed with basal forage), a model group (fed with high fat forage), an EA group (fed with high fat forage + EA treatment), a western medicine group (fed with high fat forage + Pravastatin sodium). Contents of serum total cholesterol (TC), triacylglycerol (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), endothelin (ET), nitric oxide (NO) and calcitonin gene-related peptide (CGRP) were determined before and after treatment.</p><p><b>RESULTS</b>Compared with the normal group, the body weight, levels of TC, TG, LDL-C and ET were significantly elevated (P < 0.05, P < 0.01) and the levels of HDL-C, NO and CGRP were significantly decreased (P < 0.05) in the model group; compared with the model group, the body weight, levels of TC, TG and LDL-C were significantly decreased (P < 0.01) and the levels of NO and CGRP were significantly increased in the western medicine group and the EA group (P < 0.01, P < 0.05); compared with the EA group, HDL-C level significantly increased in the western medicine group (P < 0.01), and ET level decreased in the EA group and the western medicine group with no significant difference between the two groups (P > 0.05).</p><p><b>CONCLUSION</b>Both EA and Pravastatin sodium have better benign regulative effects on TC, TG, LDL-C, NO and CGRP and can decrease ET level to a certain extent in the rat of hyperlipidemia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Blood
/
Acupuncture Points
/
Calcitonin Gene-Related Peptide
/
Electroacupuncture
/
Endothelins
/
Rats, Wistar
/
Hyperlipidemias
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Cholesterol, HDL
/
Cholesterol, LDL
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Acupuncture & Moxibustion
Year:
2008
Type:
Article
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