Oral-maxillofacial malignant tumors: an initial study with in vivo single-voxel 1H MR spectroscopy / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 18-20, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-292997
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the possibility of using single-voxel (1)H MR spectroscopy to evaluate malignant soft tissue tumors of oral-maxillofacial region.</p><p><b>METHODS</b>Forty-two patients with oral-maxillofacial malignant tumors, examined by single-voxel (1)H MR spectroscopy at a 1.5 T MR unit before treatment and confirmed by histo-pathological examination, were retrospectively studied. The localization for (1)H MR spectroscopy was used with a point-resolved spectroscopy (PRESS) at echo time of 144 ms. Choline (Cho), one of tumor's metabolites, was considered as a criterion to assess the malignant tumors.</p><p><b>RESULTS</b>Of 42 oral-maxillofacial malignant tumors, the Cho peak was identified in 37 lesions, including 15 of 17 squamous cell carcinomas, 9 of 12 salivary carcinomas, and 13 of 13 sarcomas and non-Hodgkin lymphomas.</p><p><b>CONCLUSIONS</b>Single-voxel (1)H MR spectroscopy might provide useful information for the assessment of malignant soft tissue tumors in the oral-maxillofacial region. Most malignant tumors in this study were characteristic of containing Cho metabolites. The Cho peak was more frequently recognized in the sarcomas and non-Hodgkin lymphomas than in the carcinomas.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Facial Neoplasms
/
Mouth Neoplasms
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Choline
/
Diagnosis
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2007
Type:
Article
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